Severe combined immunodeficiency presented with septic arthritis: A case report

A case of severe combined immunodeficiency presenting with CMV pneumonia

A five month-old girl was admitted in Ali Asghar Children’s Hospital with a history of three months of fever, cough and dyspnea that her symptoms have exacerbated since two weeks before admission. She was the first child of the family born to consanguineous parents. She was clinically healthy in the past and had gained weight normally and undergone vaccination program with no complication unti...

Severe combined immunodeficiency syndrome with RAG1 mutation gene - case report

Results ACOA, 3 months, female, born cesarean with 38 weeks. She had the following vaccines: BCG, hepatitis B, VIP / VOP, tetravalent rotavirus, pneumococcus and menigococo. The patient had daily fever for 4 days, oliguria, dyspnea, and diarrhea with severe septic shock and respiratory failure. The patient remained hospitalized in intensive care for 50 days with tracheal intubation for 23 days....

multifocal dactylitis as a consequence of bacillus calmette-guérin vaccination in a patient with severe combined immunodeficiency: a case report

introduction bacillus calmette-guérin (bcg) vaccine, a live attenuated mycobacterium bovis strain, is administrated to all newborn infants in endemic regions according to the current world health organization (who) recommendation. case presentation we report a 10-month-boy who was a known case of severe combined immunodeficiency (scid) admitted with multi-focal fusiform painful swelling in his ...

Hyper-IgM Immunodeficiency with Enamel Defects: a Case Report

Background: Hyper-Immunoglobulin M (IgM) syndrome (HIGM) is a rare primary immunodeficiency in which defective B-cell isotype switching results in a phenotype characterized by elevated or normal serum IgM levels and low levels of other Ig classes, leading to an increased susceptibility to infection, neutropenia, autoimmune disorders, and malignancies. In this disease, a mutation occurs in the C...

septic arthritis caused by kingella kingae: a case report

Chronic Inflammatory Demyelinating Polyneuropathy in a Patient with Adenosine Deaminase Deficiency Severe Combined Immunodeficiency: Case Report

Adenosine deaminase deficiency is a type of severe combined immunodeficiency that involves about 15% of all SCID cases. This form of SCID has low B cells, T cells, and NK cells. This condition is complex with many possible complications including neurological abnormalities. Guillainbarré syndrome is an acute inflammatory disease of the peripheral nerves that involves an autoimmune attack on mye...